Codeine Dependency & Addiction Treatment

Codeine Withdrawal Treatment Center

ANR Clinic is Now in the US

Codeine is an opiate used to treat mild to moderate pain, coughing, and diarrhea. To make it more effective, it is often combined with paracetamol (Acetaminophen) or some nonsteroidal anti-inflammatory drug (NSAIDs) such as aspirin or ibuprofen. It usually starts working in half an hour and has a maximum effect in two hours, lasting for four to six hours. Although less potent, Codeine has similar effects to morphine and is considered a gateway drug to other opiates, including morphine and even heroin. Codeine is metabolized by the liver into morphine. Codeine makes up about two percent of opium. Codeine is the most commonly used opiate. It is estimated that 33 million people use Codeine every year. Street names for Codeine include cough syrup, schoolboy, coties, and t-three’s.

Codeine or 3-methylmorphine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is often sold as a salt in the form of either codeine sulfate or codeine phosphate in the United States and Australia; codeine hydrochloride is more common worldwide and the citrate, hydroiodide, hydrobromide, tartrate, and other salts are also seen. Codeine is the second-most predominant alkaloid in opium, at up to three percent. Although codeine can be extracted from natural sources, a semi-synthetic process is the primary source of codeine for pharmaceutical use. It is considered the prototype of the weak to midrange opioids. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. It is the most commonly taken opiate. It is on the WHO Model List of Essential Medicines, a list of the most important medication needed in a basic health system.

The World Health Organization’s List of Essential Medicines considers Codeine as one of the safest and most effective medicines needed in a health system. Codeine is Schedule II/IIN Controlled Substances (2/2N), according to the Drug Enforcement Administration. Substances in this schedule have a high potential for abuse which may lead to severe psychological or physical dependence. Cough syrups, such as Robitussin, which contain no more than 200 milligrams of Codeine per 100 milliliters, are schedule V and are considered to have a low potential for abuse.

  • Narcotic
  • It can treat pain and cough.
  • Controlled substance
  • High risk for addiction and dependence. Can cause respiratory distress and death when taken in high doses or when combined with other substances, especially alcohol.
  • Availability: Prescription needed
  • Pregnancy: Consult a doctor
  • Alcohol: Avoid. Very serious interactions can occur
  • Drug class: Opioid

The effects of Codeine

Besides pain relief and suppressing cough, Codeine causes

  •  Euphoria
  •   Apathy
  •  Drowsiness
  •   Relaxation

Although many people consider Codeine harmless, at high enough doses, Codeine use can lead to respiratory failure, coma, and even death. This risk exponentially increased when Codeine combined with other central nervous system depressants such as alcohol or other opioids.
Common side effects include:

Common side effects include:

  • Vomiting 
  • Constipation
  • Itchiness
  • Lightheadedness
  • Drowsiness

Serious side effects may include Breathing difficulties and finally, addiction and dependency.

Addiction to Codeine

People may develop an addiction to Codeine after continued use and/or abuse of the drug in its cough medicine or pill form. Codeine users often get a false sense of security because Codeine is not considered as powerful or addictive as other opiate family members such as heroin. But, regardless of its potency, each opioid, including Codeine, has the potential for causing dependency and addiction because it affects the brain exactly in the same way. This effect has to do with neuroadaptation. Our body produces endorphins as a response to various stimuli – pain, pleasure, stress, excitement, etc. Endorphins reduce pain and cause a feeling of relaxation. Opioids have the same effect – they affect endorphin receptors, causing the body to adapt and stop producing natural endorphins. As more opioids introduced into the body, the more endorphin receptors are created, demanding more opioids, creating a never-ending cycle of demand and supply. Person’s need for more opioids creates powerful neuro-biological craving, a constant demand for more opioids.

Codeine is easily available, often without a prescription, especially as a cough syrup. Codeine cough syrup is used to make Purple Drank. Purple Drank is a recreational form of the cough syrup made by mixing prescription-grade cough syrup that has Codeine with soft drinks, such as Sprite or Mountain Dew, to be used in large doses. Purple Drank is also called lean, syrup, and sizzurp.

Signs of Codeine abuse 

Some signs of Codeine abuse include:

  • Drowsiness
  • Slurred speech
  • Short attention span
  • Impaired judgment
  • Dilated pupils
  • Lack of coordination
  • Apathetic behavior

Long term signs of Codeine abuse include:

  • Depression
  • Anxiety
  • Fatigue
  • Impaired memory
  • Liver damage
  • Kidney damage
  • Muscle spasms
  • Death

Codeine withdrawal symptoms

As with other opiates, prolonged use of Codeine can cause dependence. Once the dependence has developed, if a person suddenly stops the medication or lowers the dose, he or she may experience withdrawal symptoms. Symptoms of Codeine withdrawal include:

  • Drug craving
  • Runny nose
  • Yawning
  • Sweating
  • Insomnia, 
  • Weakness, 
  • Stomach cramps 
  • Nausea
  • Vomiting
  • Diarrhea
  • Muscle spasms
  • Chills
  • irritability and Pain.

Codeine withdrawal symptoms are very similar to the symptoms of withdrawal of other opiates such as morphine. Codeine withdrawal symptoms are usually not life-threatening, making some people try to quit cold-turkey. Unfortunately, unpleasant withdrawal symptoms often lead to relapse.

Schedule a FREE consultation with one of our physicians today

Codeine Withdrawal Timeline

The withdrawal process from Codeine abuse is long and arduous, whether a person is trying to do it ‘cold turkey’ or under medical supervision.

Days 0-4   The first four days of the withdrawal are brutal while physical symptoms peak. A person often experiences nausea, insomnia, muscle pain, restless legs, headaches, diarrhea, sweating, and vomiting. 

Days 5-7    Most physical symptoms will start to fade during this period. On the other hand, psychological symptoms such as depression, start showing up. Because of excessive sweating, diarrhea, or lack of fluids during the first few days, a person might get dehydrated.

Days 8-45   During this period, almost all Codeine withdrawal symptoms are over except for depression. Depression and Codeine cravings often last for months.

Codeine withdrawal symptoms vary from person to person, as does the severity and duration of the process of withdrawal. The timeline and severity of an individual’s withdrawal process can depend on:

  • How long they used Codeine;
  • What is the average dose of Codeine they took;
  • How often they used Codeine;
  • Did they combine Codeine with alcohol or other opioids;
  • Their mental health;
  • Their general health;
  • Their gender;
  • Their body weight;
  • How they took Codeine.

Accelerated Neuro-Regulation or  ANR treatment offers radically different results. The entire procedure lasts four to five hours, requiring a patient to stay in a specialized hospital for about 30 hours. There is no danger of relapse since the procedure treats the root causes of addiction on the physical, biological level.

Detox from Codeine

Detox from Codeine and other opioids cannot be successful unless a person suffering from opioid dependency understands that opioid dependence or addiction is a medical condition, and it is not caused by psychological triggers. This physical disorder is caused by the breakdown of the body’s natural endorphin production to balance itself after being disrupted by the introduction of external opioids. This disorder must be treated by modern medicine. This acute disorder has little to do with someone having an addictive personality. In fact, addictive tendencies are the result of patients coping with their opioid dependency or addiction.

These physical causes of opioid addiction, the roots of addiction, stem from the fact that our bodies naturally produce endorphins as we experience triggers such as pain, pleasure, or stress. But opioids also affect the production of endorphins, and once we start introducing opioids into our body, the body stops producing natural opioids. The more opioids are introduced into the body; the more endorphin receptors are produced. These additional receptors demand more opioids in a vicious cycle of misery and craving. Once we understand this, we also understand why fighting the addiction is so hard and why the pain of withdrawal is so vicious. The only way to stop it is to restore the endorphin receptor balance, to bring it to its original state.

The understanding of this process, the modulation, and regulation of the endorphin system is the foundation of Accelerated Neuro-Regulation or the  ANR treatment. ANR is now the new standard of opioid withdrawal treatment. It is the only treatment that treats the root of the dependency.

Fast & Rapid Codeine Detox

In the 90s, Dr. Waismann radically changed opioid symptoms withdrawal treatment and opioid detox by developing the concept of” Rapid Detox.” Thanks to Dr. Waismann’s success, this method was adopted by many opioid treatment centers. They have been implementing Rapid Detox without enough information, knowledge, or experience for its safe and effective use to treat opioid addiction. As a consequence, Rapid Detox has a history of very poor results and even serious health complications. Detox centers that utilize Rapid Detox do not make a crucial difference Dr. Waismann made between opioid addiction and opioid dependency, consequently not addressing the root cause of the opioid dependency.

The ANR Treatment based on advanced scientific research and medical advancements, as well as 30 years of clinical work of Doctor Andre Waismann. It is Dr. Waismann who has identified the biological, physical roots of opioid dependency in the ’90s. During his illustrious career, Dr. Waismann has given numerous lectures and educated health professionals all over the world. The success of Dr. Waismann’s ANR is directly related to the ability to evaluate the balance of endorphin-receptor of each patient and being able to bring each individual to his or her optimal chemical balance. ANR is the only treatment in the world that addresses the root of opioid addiction.

Codeine Addiction Treatment

Codeine dependency or addiction, like addiction to any other opioid, is a medical, physical condition. When Codeine is used or abused for an extended period of time, the opioid receptors go through neuroadaptation. The natural production of endorphins is affected by opioids, the body develops a tolerance to the increased doses of Codeine and increased doses of Codeine are necessary to create the same effect. The neuroadaptation causes a powerful craving for Codeine in order to feel balanced. When not enough Codeine is available, a person starts feeling withdrawal symptoms. At that point, a person would do anything to get more drug and interpersonal and professional problems start.

ANR therapy focuses on this biological lack of balance in the endorphin production system. The procedure starts with an induced withdrawal to return the opioid receptors and endogenous endorphins production to a normal level for that person, a level that existed before the person started introducing opioid drugs into the system. The ANR method brings the central nervous system back in balance using an individualized approach based on each patient’s physical condition and endorphin-receptor balance.

Once ANR achieves that balance, the biological causes for the opioid cravings are eliminated and the person is free of addiction without the danger of relapse. The treatment is carried out under sedation to eliminate the discomfort from the withdrawal symptoms.

Codeine Rehab near me/you

ANR therapy is now available at the ANR Clinic in the USA in Tampa, Florida as well as in the ANR clinics in Switzerland and Israel. You can contact them to schedule an appointment at [email protected] or phone at +1 (813) 750-7470

Codeine Rehab Facility

The ANR procedure itself, which includes dealing with withdrawal symptoms and Codeine addiction treatment lasts about five hours. It requires the patient to be hospitalized for a period of about 30 hours. In the US the treatment takes place at Landmark Hospital in Naples, Florida.

The treatment starts with hospitalization in the ANR unit of the hospital. The patients are medically evaluated, undergo full laboratory screening and clinical examination before the treatment can commence. The medical evaluation includes checking Various aspects such as blood pressure, weight, electrolyte levels, liver functions, kidney functions, blood count, and electrocardiogram.

A patient receives pre-medication during this period to prepare them for the procedure. Once preparations are completed, the patient is placed under total sedation and is monitored for four to five hours by the intensive care nurses, anesthesiologists, and Dr. Waismann himself.

During this treatment phase, the body’s opioid receptors are cleansed and blocked with Naltrexone according to the patient’s specific receptor status and are carefully tailored for each individual.

This person goes through withdrawal symptoms while under sedation. This allows the patient to be relieved of their opioid dependency without suffering the unpleasant and painful opioid withdrawal symptoms. The process continues until the patient’s endorphin system is balanced, the withdrawal symptoms are eliminated, and there is no more need for sedation.

The recovery starts right after the patient is awakened. He or she will continue to be evaluated and Observed overnight. The medical staff continues with adjustments to the patients’ endorphin-receptor balance during the phase as required.

Patients are asked to remain at the hospital for one or two days after treatment in order to be monitored while they are recovering. The patients at that time receive medical advice and are encouraged to regain their strength while their body continues to return to its natural rate of endorphin production. Patients are then discharged from the hospital free of opioid dependence, to enjoy a normal life without any opioid cravings and the danger of relapse.

Dr. Waismann’s Accelerated Neuroregulation addresses the opioid dependency and addiction from a modern scientific and medical perspective. He brought the treatment of opioid addiction into a new era, giving hope to thousands of opioid abusers. At the same time, he destroyed the conventional approach to opioid dependence and addiction treatment that include replacement therapy, long-term in-house rehabilitation, and detoxification. He replaced it with the new standard of opioid dependence and addiction – Accelerated Neuroregulation— ANR. More than 24,000 patients worldwide are witnesses to the uncompromising success and safety standards of ANR.


  1. Codeine Compound Summary. National Library of Medicine, National Center for Biotechnology Information. Retrieved Apr 13, 2020
  2. Drug Enforcement Administration. Controlled Substance Schedules. Retrieved Apr 13, 2020
  3. Understanding Codeine. Addiction Center. Retrieved Apr 13, 2020
  4. Roussin, Anne, et al. Misuse and Dependence on Non-Prescription Codeine Analgesics or Sedative H1 Antihistamines by Adults: A Cross-Sectional Investigation in France. PLoS One. 2013; 8(10): Published online 2013 Oct 3.
  5. Retrieved on Apr 13, 2020
  6. What is ANR? Retrieved on Apr 13, 2020.
  7. WHO Model List of Essential Medicines. Wikipedia. Retrieved on Apr 13, 2020

Become Codeine Free

Schedule a FREE consultation with one of our physicians today

About Author