How long does Codeine stay in your system?

Codeine is an opiate used to treat mild to moderate pain, as well as coughing. It is a prescription medication commonly in pill form, or a syrup. Codeine is meant to be taken every 4 hours as needed. Codeine can remain active in the bloodstream for up to 12 hours, and it often takes about 24 hours to fully process out of the body (More on Codeine withdrawal).

Codeine’s Half Life

How long a drug remains active in the system is its half-life, which is half the duration of time the drug is actively working. Codeine has a half-life of about 3 hours, meaning this is the amount of time it takes for half a dose of Codeine to leave one’s system. 

How long does Codeine stay in your system?

  • Blood: Up to 24 hours
  • Saliva: Up to 21 hours
  • Urine: Up to 48 hours
  • Hair: Up to 10 weeks

Factors That Determine How Long Codeine Stays in the System

Circumstances that influence how much codeine is in a person’s body at any given time, such age, height, weight, and body mass index (BMI). The quantity of the drug taken, as well as the time scale also play a major role. If someone has been abusing Codeine by taking high doses for a long period of time, it may take longer than average to remove the drug from a person’s body.


In conclusion, the time scale that codeine remains in someone’s system rests on a few different elements, such as the type of drug test taken and individual circumstances of the patient. Different drug tests may provide different time frames. The dosage, as well as the timeframe the patient has been using the Codeine also determines how much longer the drug remains in the system.